Reprezinta numarul de niveluri diferite ale unui parametru de intrare. Majoritatea planurilor experimentale (factoriale) se refera la 2 (-1, +1) sau 3 (-1, 0, +1) niveluri de variatie. Cu toate acestea, experimentul central compus are de obicei 5 niveluri de variatie (-?2, -1, 0, +1, +?2). Planurile de proiectare experimentala mai complexe pot avea chiar mai multe niveluri de variatie, in timp ce de ex. planurile factoriale fractionate reduc numarul de rulari experimentale necesare in functie de anumite reguli.
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